Standards and Quality System Requirements For IVD Business

ISO (International organization for Standardization)tool available to you to meet the quality system
& CEN (European committee for standardsation)requirement and there are a number of really
are two main professional bodies for formulatingcompelling reasons to apply ISO 13485.
standards. Standards can be described as vertical orFirst, If you are in compliance with ISO 13485:2003,
horizontal, depending on how broad they are. Ayou are presumed to be in compliance with the
vertical standard is specific to a device and aquality system requirements of these directives.
horizontal standard applies to a wide range ofSecond why reinvent the wheel? ISO 13485 :2003 is
devices. Example of common horizontal standards aredesigned especially for medical device companies.
ISO 13485 and ISO 14971. An example of a verticalThird, ISO 13485:2003 is recognized worldwide, and
standard is ISO 7197:2006, which deals withyour certification automatically improves the
neosurgical implants. Following is a brief discussionperception of your company and its products.
about the horizontal standards most often applied toStandards are not permanent and often updated or
medical device companies. ISO 13485:2003-Qualityreplaced by new one over the due period.
system: ISO 13485 was adopted in Europe in 1996Following are some examples of standards:
and is a modified version of ISO 9001 but withEN60601- ELECTRICAL SAFETY
additional requirements especially tailored for theAny medical device company that makes a device
medical device industry. Most people believe that ISOwith an electrical component knows about EN60601
13485:2003 and many standards in general, is aseries. This standard deals with electrical safety and
requirement, but this is not true. It is voluntary in theelectromagnetic compatibility(EMC). (CE marking)
context of the European directives for medicalEN 980- Use of symbols on labeling
devices. It is true that you are required to meet theISO 14971- RISK MANAGEMENT
quality system requirements outlined in theISO 1497:2000 sets a formal process for dealing with
directives(Annex 2 and Annex 5 specifically), but howrisk and focuses on how your company can produce
you are going to meet those quality systemsafer products.
requirements is left to you, ISO 13485 is a voluntary